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Cell Biology E-Book

Authors: Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, Graham Johnson Publisher: Elsevier Health Sciences Publication date: 2016 Publication language: Angielski Number of pages: 908 EAN: 9780323400022 ISBN: 9780323400022 Category: Pre-clinical medicine: basic sciences Publisher's index: C2014-0-00272-9 Bibliographic note: Graham Johnson is a computational biologist and Certified Medical Illustrator (CMI) with approx. 20 years of professional experience. He is Director of the Animated Cell at the Allen Institute. Before the Allen Institute, Johnson’s lab in the California Institute for Quantitative Biosciences at the University of California, San Francisco worked to generate, simulate and visualize molecular models of cells. His lab’s Mesoscope project and his team at Allen Institute continue this mission by uniting biologists, programmers and artists to interoperate the computational tools of science and art.

Description

The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.

  • Clearly written format incorporates rich illustrations, diagrams, and charts.
  • Uses real examples to illustrate key cell biology concepts.
  • Includes beneficial cell physiology coverage.
  • Clinically oriented text relates cell biology to pathophysiology and medicine.
  • Takes a mechanistic approach to molecular processes.
  • Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing.
  • Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation.
  • Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing.
  • Includes hundreds of new and updated diagrams and micrographs, plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.

Author's affiliation

Thomas D. Pollard: Professor, Department of Molecular, Cellular,
William C. Earnshaw: Professor and Wellcome Principal Fellow, Inst
Jennifer Lippincott-Schwartz: Head, Section on Organelle Biology, Cell Biol
Graham Johnson: Director, Animated Cell, Allen Institute for Cell Biology, Seattle, Washington;, QB3 Faculty Fellow, University of California, San Francisco, San Francisco, California